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Laishun Chen Selected Research

Levomilnacipran

10/2015Evaluation of Cytochrome P450 (CYP) 3A4-Based Interactions of Levomilnacipran with Ketoconazole, Carbamazepine or Alprazolam in Healthy Subjects.
9/2015Levomilnacipran Pharmacokinetics in Healthy Volunteers Versus Patients with Major Depressive Disorder and Implications for Norepinephrine and Serotonin Reuptake Inhibition.
1/2015Effect of renal impairment on the pharmacokinetics of levomilnacipran following a single oral dose of levomilnacipran extended-release capsule in humans.
1/2015Disposition and metabolism of [14C]-levomilnacipran, a serotonin and norepinephrine reuptake inhibitor, in humans, monkeys, and rats.
5/2014Effect of hepatic impairment on the pharmacokinetics of levomilnacipran following a single oral dose of a levomilnacipran extended-release capsule in human participants.

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Laishun Chen Research Topics

Disease

5Major Depressive Disorder (Major Depressive Disorders)
10/2015 - 05/2014
2Rheumatoid Arthritis
01/2011 - 11/2009
1Alzheimer Disease (Alzheimer's Disease)
07/2015
1Arthritis (Polyarthritis)
11/2009
1Experimental Arthritis
11/2009
1Neoplasms (Cancer)
10/2002

Drug/Important Bio-Agent (IBA)

5LevomilnacipranIBA
10/2015 - 05/2014
3Norepinephrine (Noradrenaline)FDA LinkGeneric
10/2015 - 05/2014
3Serotonin (5 Hydroxytryptamine)IBA
10/2015 - 05/2014
1Pharmaceutical PreparationsIBA
07/2015
1Donepezil (Aricept)FDA LinkGeneric
07/2015
1Memantine (Namenda)FDA Link
07/2015
1benzocycloheptapyridineIBA
01/2011
1Dihydrotachysterol (AT 10)IBA
11/2009
14(2'- aminoethyl)amino- 1,8- dimethylimidazo(1,2- a)quinoxalineIBA
11/2009
12- methoxy- N- ((6- (1- methyl- 4- (methylamino)- 1,6- dihydroimiazo(4,5- d)pyrrolo(2,3- b)pyridin- 7- yl)pyridin- 2- yl)methyl)acetamideIBA
11/2009
1LipopolysaccharidesIBA
11/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2009
1I-kappa B KinaseIBA
11/2009
1PolyphenolsIBA
10/2002
1TeaIBA
10/2002